Each tablet contains 1250 mg of Calcium Carbonate USP (Coral source) equivalent to 500 mg of elemental Calcium and Vitamin D3 200 IU as Cholecalciferol USP.
Probal-D provides Calcium and Vitamin D3 where Calcium Carbonate is sourced from Coral origin. The Calcium Carbonate from Coral has a chemical structure that is very similar to the composition of human bone. Coral Calcium is similar to other sources but ensures better absorption. Vitamin D3 aids in the absorption of Calcium from GI tract and helps to maintain Calcium balance in the body.
Probal-D is indicated in-
The treatment and prevention of osteoporosis, osteomalacia, rickets, tetany and parathyroid diseases
Pregnancy & lactation due to increased demand
Preeclampsia during pregnancy
Inadequate intake of Calcium in childhood
As phosphate binder in chronic renal failure
Dosage & Administrations:
One tablet once or twice daily with plenty of water or as directed by the physician. Taking in full stomach ensures better absorption.
Warning & Precautions:
In presence of mild hypercalciuria, careful monitoring with reduction of dose may be needed. Plasma and serum calcium level should be monitored in mild to moderate renal impairment and also in case of long term use. Patients with renal stone or with such previous history should also take precaution.
Flatulence, diarrhoea, constipation, upper GI discomfort etc. are rare manifestation. Hypercalcemia due to prolong use has rarely been reported.
Oral Calcium can reduce the absorption of Tetracycline & Fluoride preparations and minimum 3 hours time should be allowed between ingestion of these medications. Thiazide diuretics reduces the renal excretion of Calcium. Phenytoin, Barbiturates, Glucocorticoids may induce metabolism of Vitamin D3. Concomitant ingestion of certain foods like spinach, cereals, milk and its derivatives may reduce the intestinal uptake of Calcium.
Use in Special Groups:
Normal requirement of Calcium and Vitamin D3 are raised during pregnancy and lactation. Probal-D can be given to pregnant and lactating mothers as per recommendation of physician.
Hypersensitivity to any of the components, hypercalcemia resulting from overdose of Vitamin D3, hyperparathyroidism, bone metastases, severe renal insufficiency, severe hypercalciuria, renal calculi etc.
Store at below 30º C in a dry place protected from light. Keep out of reach of children.
Each box contains 40 tablets in Alu-PVDC blister pack.